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B12 injections are contraindicated for individuals with Lebers hereditary optic neuropathy, severe kidney disease, known cobalt or cobalamin allergy, and polycythemia vera
Comments submitted after July 9 but before the July 22 docket closure will still be considered by FDA, but will not go directly to the Committee
Typical assay ranges span 100 nM to 1 M, adjusted per cell type and endpoint measures
The neurogenesis data is striking
Cautions: Do not give B12 injections to someone with a known hypersensitivity to cyanocobalamin, hydroxocobalamin, or cobalt
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